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Vancomycin resistant Staphylococcus aureus ... | 疾病管制署傳染病

Vancomycin resistant Staphylococcus aureus ...

由YCong著作·2020·被引用64次—EffectiveantibioticforVRSAFortunately,VRSAisolatesaresusceptibletomultipleantibiotics[78](TableS1),whichmadeantibacterialtherapy ...

 Vancomycin resistant Staphylococcus aureus ...

Graphical abstract

Keywords: Vancomycin-resistant Staphylococcus aureus, Treatment, Vancomycin, vanA cluster

Abstract

The infection caused by methicillin-resistant Staphylococcus aureus (MRSA) is a global threat to public health. Vancomycin remains one of the first-line drugs for the treatment of MRSA infections. However, S. aureus isolates with complete resistance to vancomycin have emerged in recent years. Vancomycin-resistant S. aureus (VRSA) is mediated by a vanA gene cluster, which is transferred from vancomycin-resistant enterococcus. Since the first VRSA isolate was recovered from Michigan, USA in 2002, 52 VRSA strains have been isolated worldwide. In this paper, we review the latest progresses in VRSA, highlighting its resistance mechanism, characteristics of VRSA infections, as well as clinical treatments.

Introduction

Due to the metabolic versatility and pharmic resistance, Staphylococcus aureus is well adapted i...

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VRSA | 疾病管制署傳染病
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Vancomycin | 疾病管制署傳染病
The approach is to treat with at least one agent to which VISA/VRSA is known to be susceptible by in vitro testing. The agents that are used include daptomycin, ... Read More
Methicillin and Vancomycin Resistant S. aureus in ... | 疾病管制署傳染病
由 PS Loomba 著作 · 2010 · 被引用 182 次 — There are only limited drugs available for the treatment of VRSA. Quinupristin-​dalfopristin and linezolid are two of the newer antimicrobial agents currently ... Read More
Vancomycin resistant Staphylococcus aureus ... | 疾病管制署傳染病
由 Y Cong 著作 · 2020 · 被引用 64 次 — Effective antibiotic for VRSA Fortunately, VRSA isolates are susceptible to multiple antibiotics [78] (Table S1), which made antibacterial therapy ... Read More
Focus | 疾病管制署傳染病
由 WA McGuinness 著作 · 2017 · 被引用 350 次 — aureus (VRSA). Despite being approved for use in humans in 1958, vancomycin became an antibiotic of choice for treatment of MRSA infections ... Read More
Vancomycin resistant Staphylococcus aureus infections | 疾病管制署傳染病
由 Y Cong 著作 · 2020 · 被引用 64 次 — Effective antibiotic for VRSA Fortunately, VRSA isolates are susceptible to multiple antibiotics [78] (Table S1), which made antibacterial therapy an effective option ... Read More
Vancomycin | 疾病管制署傳染病
The mainstay of VRSA treatment includes treating underlying co-morbidities and antimicrobial therapy combined with appropriate surgical intervention as ... Read More
Vancomycin Resistance in Staphylococcus aureus | 疾病管制署傳染病
由 WA McGuinness 著作 · 2017 · 被引用 353 次 — Although treatment of VRSA infections is challenging, the total number of human VRSA infections to date is limited (14 in the U.S.). By comparison ... Read More
Treatment of bacteraemia | 疾病管制署傳染病
由 IM Gould 著作 · 2013 · 被引用 61 次 — Treatment of bacteraemia: meticillin-resistant Staphylococcus aureus (MRSA) to vancomycin-resistant S. aureus (VRSA). Int J Antimicrob ... Read More
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